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KMID : 0617819930030010167
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Journal of Wonkwang Oriental Medicine
1993 Volume.3 No. 1 p.167 ~ p.179
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Study on the Difference of the Saponin Content in Platyxodi Radix of Various kinds
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Abstract
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First, Platycodi Radix in this study was divided according to natural Platycodi Radix and cultured Platycodi Radix(White, claret), with or without peeling. And then comparative study was made through analyzing the extract, Crude Saponin content and Crude Saponin component by HPLC.
The results were as follows :
1. Generally the extract in Platycodi Radix was more in the natural Platycodi Radix and the cultured Platycodi Radix without peeling than that with peeling. It was extremely much in the cultured claret Platycodi Radix with peeling had the least extract.
2. Crude Saponin Content was more in the natural Platycodi Radix and the cultured Platycodi Radix without peeling than with peeling, extremely much in the natural Platycodi Radix without peeling and the cultured claret Platycodi Radix with peeling had the least content.
3. Prosapogenin content increased in the natural Platycodi Radix and the cultured Platycodi Radix without peeling than that with peeling and it was most extremely in the natural with and without peeling. Also the cultured claret Platycodi Radix had the least content.
4. The analysis of Crude Saponin content in the Platycodi Radix by HPLC showed that 8 kinds of saponin were in the cultured white Platycodi Radix with peeling, 9 without peeling, 9 in the cultured claret with peeling, 10 without peeling, 10 in the natural with peeling and 11 without peeling.
5. The analysis of Prosapogenin by HPLC showed that 6 kinds fo prosapogenin were in the cultured white Platycodi Radix with peeling, 7 without peeling, 3 in the cultured claret with peeling, 5 without peeling and 4 in the natural with peeling, 5 without peeling.
6. The analysis of Free sugar shows that 3 kinds of Sugar were in the cultured white Platycodi Radix with peeling, 5 without peeling 3 the cultured claret with peeling, 5 without peeling, 4 in the natural with peeling, 5 without peeling.
From the above results, the content of Crude Saponin, Prosapogenin and all sorts of Saponin, Prosapogenin, Free Sugar were variable according to the natural Platycodi Radix and the cultured white and claret with or without peeling. Therefore, it is recommended that there should be more studies on the Saponin and Prosapogenin of various kinds to use a dose and an efficacy of a remedy in accordance with the Platycodi Radix of different kinds, systematically.
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